RHOMBENCEPHALITIS POSSIBLY CAUSED BY MYCOPLASMA PNEUMONIAE

Authors

  • Aamir Khan khyber medical university peshawar
  • Ayaz Ul Haq Lady Reading Hospital Peshawar
  • Hira Hamid Lady Reading Hospital Peshawar
  • Tanvir Fatima Lady Reading Hospital Peshawar
  • Shakira Adnan Lady Reading Hospital Peshawar

DOI:

https://doi.org/10.55519/JAMC-03-9417

Keywords:

Mycoplasma pneumoiae, meningoencephalitis, rhombencephalitis

Abstract

We report a rare case of encephalitis that is not often described in clinical settings in neurology. Our case was 11-year-old female patient who had presented with features of meningoencephalitis, but not responded to the conventional treatment. Her magnetic resonance imaging revealed lesions in thalami, cerebellum and brainstem. The differentials in this age were infective and inflammatory causes of meningoencephalitis and acute disseminated encephalomyelitis (ADEM). Paraneoplastic was another differential. Mycoplasma serology came out positive. As a result, diagnosis of mycoplasma pneumoiae associated Rhombencephalitis was made based on diagnosis of exclusion.

Author Biographies

Ayaz Ul Haq, Lady Reading Hospital Peshawar

ASSISTANT PROFESSOR NEUROLOGY

Hira Hamid, Lady Reading Hospital Peshawar

POST GRADUATE RESIDENT NEUROLOGY LRH

Tanvir Fatima, Lady Reading Hospital Peshawar

POST GRADUATE RESIDENTT NEUROLOGY LRH

Shakira Adnan, Lady Reading Hospital Peshawar

MEDICAL OFFICER

References

Qu J, Yang C, Bao F, Chen S, Gu L, Cao B. Epidemiological characterization of respiratory tract infections caused by Mycoplasma pneumoniae during epidemic and post-epidemic periods in North China, from 2011 to 2016. BMC Infect Dis 2018;18(1):355.

Kuwahara M, Samukawa M, Ikeda T, Morikawa M, Ueno R, Hamada Y, et al. Characterization of the neurological diseases associated with Mycoplasma pneumoniae infection and anti-glycolipid antibodies. J Neurol 2017;264(3):467–75.

D’Alonzo R, Mencaroni E, Di Genova L, Laino D, Principi N, Esposito S. Pathogenesis and Treatment of Neurologic Diseases Associated With Mycoplasma pneumoniae Infection. Front Microbiol 2018;9:2751.

Søndergaard MJ, Friis MB, Hansen DS, Jørgensen IM. Clinical manifestations in infants and children with Mycoplasma pneumoniae infection. PLoS One 2018;13(4):e019288.

Narita M. Classification of Extrapulmonary Manifestations Due to Mycoplasma pneumoniae Infection on the Basis of Possible Pathogenesis. Front Microbiol 2016;7:23.

de Groot RC, Sauteur PM, Unger WW, van Rossum AM. Things that could be Mycoplasma J infect. 2017;74:S95-100.

Özkale Y, Erol İ, Çoban-Karataş M, Alkan Ö. Optic neuritis as a presenting symptom of Mycoplasma pneumoniae infection. Turk J Pediatr 2015;57(4):401–6.

Bajantri B, Venkatram S, Diaz-Fuentes G. Mycoplasma pneumoniae: a potentially severe infection. J Clin Med Res. 2018;10(7):535.

Christo PP, Silva JS, Werneck IV, Dias SL. Rhombencephalitis possibly caused by Mycoplasma pneumoniae. Arq Neuropsiquiatr 2010;68(4):656–8.

Wei P, Bao R, Fan Y. Brainstem Encephalitis Caused by Listeria monocytogenes. Pathogens 2020;9(9):715.

Loens K, Ieven M. Mycoplasma pneumoniae: Current Knowledge on Nucleic Acid Amplification Techniques and Serological Diagnostics. Front Microbiol 2016;7:448.

Kammer J, Ziesing S, Davila LA, Bültmann E, Illsinger S, Das AM, et al. Neurological Manifestations of Mycoplasma pneumoniae Infection in Hospitalized Children and Their Long-Term Follow-Up. Neuropediatrics 2016;47(5):308–17.

Diallo IM, Boubacar S, Mansaré ML, Cissé O, Nyassindé J, Ndong ME, et al. Diagnosis Approach and Management of Rhombencephalitis: Literature Review. Clin Neurol Neurosci 2017;18;1(2):47–51.

Waites KB, Xiao L, Liu Y, Balish MF, Atkinson TP. Mycoplasma pneumoniae from the Respiratory Tract and Beyond. Clin Microbiol Rev 2017;30(3):747–809.

Bouziri A, Khaldi A, Menif K, Jaballah NB. Acute disseminated encephalomyelitis associated with Mycoplasma pneumoniae infection in children: 2 case reports. Tunis Med 2010;88(2):125–8.

Published

2022-06-21

Issue

Vol. 34 No. 3 (2022): JOURNAL OF AYUB MEDCIAL COLLEGE ABBOTTABAD

Section

CASE REPORT

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