COMPARISON OF EMERGENCY AND ELECTIVE INTERVENTION WITH SEMI-RIGID URETEROSCOPIC LITHOTRIPSY FOR PATIENTS WITH URETERAL CALCULI

Authors

  • Muhibullah Bangash The Aga Khan University Hospital, Karachi-Pakistan
  • Syed Muhammad Nazim The Aga Khan University Hospital, stadium road, Karachi- 74800.
  • Nasir Khan The Aga Khan University Hospital, Karachi-Pakistan
  • Owais Ghani The Aga Khan University Hospital, Karachi-Pakistan
  • Suniya Naeem The Aga Khan University Hospital, Karachi-Pakistan

DOI:

https://doi.org/10.55519/JAMC-01-9612

Keywords:

Calculi, Elective, Emergency, Ureter, Ureteroscopy

Abstract

Background: Ureteroscopy (URS) is a safe and highly effective treatment option for treatment of ureteral calculi. With the advancement of technology, there is also expansion of its indications including use in early or emergency setting. This study aims to compare safety and efficacy of emergency ureteroscopy (EmURS) versus elective ureteroscopy (ElURS) for ureteral stones. Methods: Patients with unilateral single radio-opaque ureteral stone who underwent semi-rigid URS from January 2008 till December 2019 were included. Patients with solitary kidney, uro-sepsis, pregnancy or pre-operative drainage with nephrostomy or JJ stent were excluded. EmURS was defined as URS being performed within 48 hours of presentation, while ElURS was defined as URS performed after failed medical expulsive therapy. Patient, stone and outcome related variables were compared in both groups. Stone free rate was defined as no evidence of stone on plain x-ray KUB after 1 week. Results: We compared 132 patients in EmURS group against 264 in ElURS group. Age, gender, comorbidities, stone location, laterality and mean stone size were comparable in both groups. EmURS had a less median operative time (p=0.05). Stone free rate achieved was 90.2% in EmURS and 87.1% in ElURS, respectively (p=0.38). Double J stent was placed in 44.7% and 46.2% of EmURS and ElURS respectively (p=0.89). Ancillary procedures were performed in 9.8% of EmURS and 11.7% of ElURS (p=0.57). Overall complication rates were reported in 7.6% in EmURS and 11.7% in ElURS (p=0.22) and most were Clavien grade 1. Conclusion: Emergency URS for ureteral stones is a safe and effective one–stage definitive treatment option for patients with acute renal colic not responding to conservative management

Author Biographies

Muhibullah Bangash, The Aga Khan University Hospital, Karachi-Pakistan

Chief Resident, Section of Urology, Department of Surgery

Syed Muhammad Nazim, The Aga Khan University Hospital, stadium road, Karachi- 74800.

Assistant Professor, Department of Surgery

Nasir Khan, The Aga Khan University Hospital, Karachi-Pakistan

Chief Resident, Section of Urology, Department of Surgery

Owais Ghani, The Aga Khan University Hospital, Karachi-Pakistan

Research Associate, Section of Urology, Department of Surgery

Suniya Naeem, The Aga Khan University Hospital, Karachi-Pakistan

Research Associate, Section of Urology, Department of Surgery.

References

Cui Y, Chen J, Zeng F, Liu P, Hu J, Li H, et al. Tamsulosin as a medical expulsive therapy for ureteral stones: a systematic review and meta-analysis of randomized controlled trials. J Urol 2019;201(5):950–5.

Mittakanti HR, Conti SL, Pao AC, Chertow GM, Liao JC, Leppert JT, et al. Unplanned Emergency Department Visits and Hospital Admissions Following Ureteroscopy: Do Ureteral Stents Make a Difference? Urology 2018;117:44–9.

Osorio L, Lima E, Soares J, Autorino R, Versos R, Lhamas A, et al. Emergency ureteroscopic management of ureteral stones: why not? Urology 2007;69(1):27–31.

Picozzi SC, Ricci C, Gaeta M, Casellato S, Stubinski R, Bozzini G, et al. Urgent ureteroscopy as first-line treatment for ureteral stones: a meta-analysis of 681 patients. Urol Res 2012;40(5):581–6.

Guercio S, Ambu A, Mangione F, Mari M, Vacca F, Bellina M. Randomized prospective trial comparing immediate versus delayed ureteroscopy for patients with ureteral calculi and normal renal function who present to the emergency department. J Endourol 2011;25(7):1137–41.

Pradère B, Doizi S, Proietti S, Brachlow J, Traxer O. Evaluation of Guidelines for Surgical Management of Urolithiasis. J Urol 2018;199(5):1267–71.

Rajadoss MP, Berry CJ, Rebekah GJ, Moses V, Keshava SN, Jacob KS, et al. Predictors of renal recovery in renal failure secondary to bilateral obstructive urolithiasis. Arab J Urol 2016;14(4):269–74.

Portis AJ, Lundquist EL, Portis JL, Glesne RE, Mercer AJ, Lundquist BA, et al. Unsuccessful Medical Expulsive Therapy: A Cost to Waiting? Urology 2016;87:25–32.

Türk C, Neisius A, Petrik A, Seitz C, Skolarikos A, Thomas K, et al. Guidelines on urolithiasis. European Association of Urology (EAU). [Internet]. 2018 [cited 2019 Nov 23]. Available from: https://uroweb.org/guideline/ Urolithiasis/

Sarica K, Tanriverdi O, Aydin M, Koyuncu H, Miroglu C. Emergency ureteroscopic removal of ureteral calculi after first colic attack: is there any advantage? Urology 2011;78(3):516–20.

Sarica K, Eryildirim B, Sahin C, Türkoğlu ÖK, Tuncer M, Coskun A, et al. Emergency management of ureteral stones: Evaluation of two different approaches with an emphasis on patients' life quality. Arch Ital Urol Androl 2016;88(3):201–5.

Zargar-Shoshtari K, Anderson W, Rice M. Role of emergency ureteroscopy in the management of ureteric stones: analysis of 394 cases. BJU Int 2015;115(6):946–50.

Hollingsworth JM, Norton EC, Kaufman SR, Smith RM, Wolf JS Jr, Hollenbeck BK. Medical expulsive therapy versus early endoscopic stone removal for acute renal colic: an instrumental variable analysis. J Urol 2013;190:882–7.

Matani YS, Al-Ghazo MA, Al-Azab RS, Hani OB, Ghalayini IF, Hani IB. Emergency versus elective ureteroscopic treatment of ureteral stones. Can Urol Assoc J 2013;7:E470–4.

Al-Ghazo MA, Ghalayini IF, Al-Azab RS, Bani Hani O, Bani-Hani I, Abuharfil M, et al. Emergency ureteroscopic lithotripsy in acute renal colic caused by ureteral calculi: a retrospective study. Urol Res 2011;39(6):497–501.

Arcaniolo D, De Sio M, Rassweiler J, Nicholas J, Lima E, Carrieri G, et al. Emergent versus delayed lithotripsy for obstructing ureteral stones: a cumulative analysis of comparative studies. Urolithiasis 2017;45(6):563–72.

Published

2022-01-01