PARAGANGLIOMA OF THE EXTERNAL AUDITORY MEATUS
Abstract
Paragangliomas are uncommon tumors, with apresumed origin from 'glomus cells' at various places
in the body. They have also been mistakenly labelled
as Glomus Jugulare tumors. The actual origin from
neural crest epithelium and its derivative structures is
often difficult to judge from the histological
appearance, as they appear more epithelial or
"endothelial" in routine light microscopic sections.
The higher resolution of the Electron Microscope as
well as special stains for neuroepithelial products will
generally resolve their nature in difficult cases. They
are different from Chemodectomas with which they
are often classified, as they do not show chromaffin
activity, the hallmark of adrenal or extra-adrenal
chromaffin tumors.
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