ANTI-HCV ANTIBODIES DETECTION-A COMPARISON BETWEEN METHODOLOGY: ELISA VS DIPSTICK ASSAY

Authors

  • Shahid Mahmood Sheikh
  • Muhammad Tayyab
  • Ghazala Jaffary
  • Tahira Tasneem
  • Abdul Sattar
  • Iftikhar Ali

Abstract

Hepatitis C accounts for 70-95% cases of post-transfusion hepatitis in different parts of the world. The high prevalenceof antibodies to hepatitis C virus (HCV) among frequently blood transfused patients (e.g. thalassaemic), those whoreceive blood products (e.g. haemophiliacs), and among intravenous drug abusers confirmed the parenteral route asthe major route of HCV infection. To promote screening of blood donors for HCV antibodies, a Dipstick HCV assaywas compared with third generation enzyme immunoassay. Fifty diagnosed cases of hepatitis C and twenty healthycontrol subjects were analyzed by both methods and hundred per cent same results were found.

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