ACUTE TRANSVERSE MYELITIS IN CHILDREN

Authors

  • Syed Asif Masood
  • Shahnaz Ibrahim

Abstract

A case of Acute Transverse Myelitis (ATM) is presented. ATM is a rare disease in childhood.The diagnosis stems from the clinical presentation, cerebrospinal fluid findings, appearance ofthe spinal cord on imaging and ruling out differential diagnoses like Guillain-Barre syndrome(GBS) and Poliomyelitis. The proposed treatment is intravenous (IV) methyl prednisolonewith variable chances of recovery. A controlled multicenter study is suggested to assessepidemiology, etiology and prognosis of ATM.Key Words: Transverse Myelitis, Sensory level, Methyl Prednisolone.

References

Defresne P, Meyer L, Tardieu M, Scalais E, Nuttin C, Bont

B.D, et al: Efficacy of high dose steroid therapy in children

with severe acute transverse myelitis. J Neurol Neurosurg

Psychiatry 2001;71:272-4.

Linssen WHJP, Gabreels FJM, Wevers RA. Infective acute

transverse myelopathy. Report of two cases. Neuropediatrics

;22:107-9.

Kalita J, Misra U.K: Neurophysiological studies in acute

transverse myelitis. J-Neurol. 2000 Dec; 247(12): 943-8.

Altrocchi P.H. Acute transverse myelopathy. Arch

Neurol.1963:9;111-9.

Choi JU, Hoffman HJ, Hendrick EB, Humphreys RP, Keith

WS. Traumatic infarction of the spinal cord in children. J

Neurosurg 1986;65:608-10.6. Linssen W.H.J.P, Praamstra P, Gabreels F.J.M, Rotteveel J.J:

Vascular insufficiency of the cervical spinal cord due to

minor trauma with hyperextension of spine in a child. Pediatr

Neurol 1990;6:123-5.7. Abramsky O, Teitlebaum D: The autoimmune features ofacute transverse myelitis. Ann Neurol 1997;2:36-40.8. Kincaid JC, Dijken ML, Myelitis and myelopathy. Baker

A.B, et al (Eds), Clinical Neurology. Hagerstown, Harper &

Row Vol 3, 1984:1-32.

Morris A.M, Elliott E.J, D'Souza R.M, Antony J, Kennett

M, Longbottom H: Acute flaccid paralysis in Australian

children. J-Paediatr-Child-Health. 2003 Jan-Feb; 39(1): 22-6.

Yavuz H, Cakir M: Transverse myelopathy: an initial

presentation of acute leukemia. Pediatr-Neurol. 2001 May;

(5): 382-4.

Knebusch M, Reiners K. Acute transverse myelitis in

childhood: nine cases and review of literature.

Developmental Medicine & Child Neurology 1998;40:631-9.

De-Goede CG: Urinary problems following acute transverse

myelitis in children. Dev-Med-Child-Neurol. 2002 Mar;

(3): 212-3.

Ganesan V, Borzyskowski M. Characteristics and course of

urinary tract dysfunction after acute transverse myelitis in.Dev Med Child Neurol 2001; 43(7): 437-5.Krishnan C, Kaplin AL, Deshpande DM, Pardo CA, Kerr

DA. Transverse Myelitis: Pathogenesis, Diagnosis and

Treatment. Frontiers in Bioscience 2004;9:1483-99.

Wilmshurst JM, Walker MC, Pohl KRE. Rapid onset

transverse myelitis in adolescence: implications for

pathogenesis and prognosis. Arch-Dis-Child 1999;80(2):

-42.