A STUDY OF RELATIONSHIP OF ABO BLOOD GROUPS WITH MYOCARDIAL INFARCTION AND ANGINA PECTORIS

Authors

  • ISRAR AHMED AKHUND
  • IRSHAD ALI ALVI
  • ASMAT KAMAL ANSARI
  • Muhammad Azhar Mughal
  • Anwar Ali Akhund

Abstract

Background: This is a comprehensive report that has determined the occurrence of Myocardial infarction and Angina pectoris in"ABO" blood group system among patients with coronary artery disease in some areas of Sindh province of Pakistan. Methods:Three hundred patients with Coronary Disease (CAD) were selected from cardiology wards of LMC hospital Hyderabad, DMChospital Karachi and PMC hospital Nawabshah. The patients were separated into two categories: myocardial infarction and anginapectoris. The patients with old myocardial infarction were also included. A careful history was taken, suggesting myocardialinfarction (MI) or angina from a standard WHO (Rose) chest pain, and an electrocardiogram showing evidence of possiblemyocardial infarction and angina, and the patient's recall of a doctor's diagnosis of M.I or angina. ABO blood grouping of abovepatients was done by simple agglutination method. Results: The blood group "A" was the commonest among myocardial infarctionand angina pectoris patients while these diseases were least in blood group "O" patients. Conclusions: This comparison shows theexistence of a direct relation between blood group antigens and coronary artery disease. It is therefore of great importance for futuregenetic studies, as present report and our previous studies give clear picture of excess and deficit of CAD in particular blood groupsof "ABO" system. This may be due to some special genetic makeup

References

Akhund I A. Alvi I.A. Hafeezullah and Ansari A K ABO blood

groups in relation to ischemic heart disease. IAMC. 1998. Vol-

No. 114-15

Akhund I A. Alvi I.A. I Hafeezullah and Ansari A.K Blood

groups and serum lipids in patients with ischemic hear!

disease, /AMC. 1998. Vol-10 No 214-18 Whincup IKJC.

Phillips A N. Shaper A O ABO blood groups and Ischemic

heart disease in British Men B.M J. 1990: 1679-1682

Njoku. Ononoghu LC. Almunan E.O. Nwanjho .1. Scrum v

lipids. ABO blood groups and sickle cell trait. Indian 1. B

Physiol. Pharmacol. 1996: 10:171-4.

Meade T.W. Cooper J A. -Stirling Y. Factor VIII. AM) blood

groups and the incidence of ischemic heart disease. Br. J.

Haematology, 1994: 88:601-7.

Tarjan - Z. Tonelli M. Duba., J. or and i - A Correlation 9

between ABO and Rh blood groups, scrum cholesterol and

ischemic heart disease in patients undergoing coronarography.

Orv Hetil; 1995; 156(5). 767-769 Allan T.M, Dawson A.A:

ABO blood groups and ischemic heart disease.

Br. Med. J. 1986; 30:377-382.

Havlik. R.J. Feinleib. M. Garrison R.J. & Kannel WB Blood

groups and coronary heart disease. I.ancet, 1969 II 269-270.

Shaper A. G. Gook D.G. & Walker M: Prevalence of ischemic

heart disease in middle aged British men. I3r Heart- I J. 1984:

: 595-605.

Shaper A. G. Gook D.G. & Walker M Recall of diagnosis b)

man with ischemic heart disease. Br Heart-.!. 1984. 51 606- a

II

Dacie JV& Lewis SM (1984): In practical Hematology

Churchill Livingstone, Edinburgh

Mourant AL: Kopec AC <& Domaniewska -. Sobzak-K

Thrombosis, hemorrhage, and other disorders of the

circulatory system In Blood groups and diseases. 1978:

Oxford University Press, Bronte-Stewart. B. Botha M C.&

Krut I. II: ABO blood groups in relation to ischemic heart

disease British Med I -1 1962. 1.1646-1650.

Nefzger M.D. Hrubeez. Chalmers T.C Venous 7

Thromboembolism and blood groups. Lancet -1. 1969. 887

Denbrough M.A Blood groups and ischemic heart disease Br.

Med J. 1962: 2 927

Medalie. J H. Levene. C Papier. C Goldbourt U Drefus, F.

Oron D Neufeld H & Kiss I: Blood groups. myocardial

infarction and angina pectoris among 10.000 adults. Nor

England Journal of Medicine 1971.285 1348-1353

Khaskheh D K Akhund A. A, Qureshi A H Distribution of j

ABO and Rhesus blood groups in The residents of. Sindh P 1

Health, 1994.31-45-50 ,

Hussain A Shaikh S a Haider M. Rashied I. Malik MR a

frequency distribution of ABO and Rhesus blond groups in

population of Baluchistan PAFM.J 2001.Vol 51 No 1 12-26

Issue

Vol. 13 No. 4 (2001): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

License

Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License  CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.

USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.

AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.