INSULIN THERAPY IN NWFP PAKISTAN

Authors

  • MAHMUD AHMAD

Abstract

The management of Type I and Type II Diabetes
Mellitus has improved because of tremendous
improvement in Insulins over the years, but
unfortunately majority of patients in our country
cannot afford these, especially the human insulin, and
are deprived of the benefits. Access to insulin should
be regular and uninterrupted.
Insulin therapy has changed the outlook of Type I -
IDDM from certain death to almost normal existence.
The discovery of Banting and Best in 1921, was the
greatest breakthrough in this field. Since then
continuous improvement in Insulins is taking place. In
I980\s Recombinant DNA origin insulin came into
use. These insulins are less antigenic, purer, better
absorbed and lesser doses are required as compared to
animal origin insulins. Human Insulin was first
product of biotechnology to enter the clinical Arena2.
By 1950 exact structure of insulin molecule was
known3. In developed countries the prognosis of
Diabetes has dramatically improved over last twenty
years with life expectancy approaching towards
normal, especially in Denmark4.

References

Skyler JS Symposium Human Insulin or recombinant

DNA origin Diabetes care 5 (2) 1-186 1983.

Skyler JS Human Insulin after Ten years. Diabetes Care

,1-3,1993.

Bliss M History of insulin Diabetes care vol 16, Pg4-7

Cathelineau. G. Implementation of the declaration of

St. Vincent diabetic Metabol. 20: 337-4, 1994.

DCCT. The diabetes control and complications trial

Research group (DCCT) J. Am. Med. Assoc-276:

- 15,1996.

UKPDS. UK prospective Diabetes study. Intensive

blood glucose control with sulphonylureas or insulin

compared to conventional treatment and risk of

complications with Type 2 Diabetes. Lancet: 352:837-

; 1998.

Mbanya JC Insulin therapy in developing countries.

Implications of chronic shortages. Int: Diab:

Monitor. 12.1; 4-6,2000

Santiago JV Lessons from diabetes control +

complications trial. Diabetes: 42, 1549-54, 1993.

King H. Insulin, availability, affordability, and

harmonization. WHO Drug, 4;219-23, 19

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How to Cite

AHMAD, M. (2001). INSULIN THERAPY IN NWFP PAKISTAN. Journal of Ayub Medical College Abbottabad, 13(3), 36–37. Retrieved from https://www.jamc.ayubmed.edu.pk/jamc/index.php/jamc/article/view/4873