PREVALENCE OF HEPATITIS B CARRIERS AND BLOOD GROUP FREQUENCY IN VOLUNTARY BLOOD DONORS
Abstract
Infection with Hepatitis B virus is a serious hazard. A study was carried out to evaluate the prevalence rate of HBsAg carrier state among a group of 200 healthy voluntary blood donors. Blood groups and haemoglobin levels were also determined. The prevalence rate for HbsAg carrier suite was 2% (males-1.09%, females11.11%). The frequency distribution of ABO blood groups was: A- 22.7%, B- 36.35%, O- 33.85%>, and AB- 7.10%. The percentage distribution of Rh antigen was: Rh+ve- 93.44% and Rh-ve- 6.56%. Haemoglobin level, mean value ±standard deviation, for males was 13.84 ±0.95 and in case of females it was 13.02±0.53. The study reveals that females exhibit greater seropositivity, group B is the commonest and males have significantly higher Hb levels. In order to estimate HBV, blood and all blood products must be tested for HbsAg. Moreover, Hepatitis B vaccine should be included in the Expanded Programme of Immunization in our country. KEYWORDS: Hepatitis B, HbsAg, Blood groups, ABO, Rh(D), HaemoglobinReferences
Deinhardt F, Abb J & Assad F. Viral hepatitis.
Bulletin of the WHO, 1983;61:203-6.
Vall Mayans M, Hall AJ, Inskip HM, et al. Risk
factors for transmission of hepatitis B virus to
Gambian children. Lancet 1990;336:1107-9.
Thursz MR, Kwiatkowski D & Alisopp CEM, et al.
Association between an MHC Class II allele and
clearance of hepatitis B virus in the Gambia. N Engl
J Med, 1995;332:1065-9.
Blumberg BS & Alter HJ. Precipitating antibodies
against a serum protein (Australia antigen in the
blood of a transfused haemophilia patient). J Clin
Inv, 1965;44:1029.
Zeldis JB, Shabib SM & Tufenkejl H. Diagnosis of
viral hepatitis (Editorial). Annals of Saudi Medicine,
; 15(1): 1-5.
Malik 1A, Tariq WVZ, Hassan ZU & Mahmood A.
Sub-classification of hepatitis B vims carriers.
JCPSP, 1996;6(1):4-5.
Attique MUH, Yousaf M, Haleem A & Hassan A.
Prevalence of hepatitis B virus in liver diseases in
Bahawalpur. JPGMI, 1990;4(1): 139-42.
Yousaf M & Yousaf N. Prevalence of hepatitis B
carriers among health care workers. Pak J Med Res,
;27:168-9.
Jabeen M, Hussain R, Siddiqui SA, Fayyaz A &
Saleem M.Prevalence of hepatitis B surface antigen
(HbsAg) in doctors, medical students and
paramedical staff working in Sir Ganga Ram
Hospital. Lahore. Pak J Med Res, 1995:34:172- 5
Alter MJ. Hadler SC & Margolis HS, et al. the
changing epidemiology of hepatitis B in United
States. JAMA, 1990;263:1218-22.
Parveen N. ABO and subgroup A in the Lahore
population. JPMA, 1987;37:200-1.
Jamal A. Ahmed MS. Ahmad A, Zafar MN & Syed
S. ABO and A subgroups in Karachi population.
JPMA, 1988;38:199-200.
Mustansar M & Ah I. Iron deficiency in women and
children specialists. Pak J Med Sci, 1995;
(4):323-5.
Hussain S, Khan AB, Ansari JK, Fazal I & Orakzai
A. Incidence and clinical aspects of hepatitis B in
naval hospital Karachi. PAFMJ, 1994;44(2):28-33.
Burney Ml. Spectrum of liver disease as studied at
the National Health Laboratories. National Seminar
on Liver Disease (Proceedings). PMRC Monograph
No 2, 1977;44.
Janjua IM & Hussain M. Hepatitis B vims surface
antigenaemia in voluntary blood donors and patients
with acute hepatitis. Pak J Med Res, 1990;29:160-2.
Malik 1A & Tariq WIJZ. Viral hepatitis in Pakistan
(Editorial). Pak J Path, 1993;4:1-5.
Lin HJ, Lai CL & Lau JYN. et al. Evidence for
intrafamilial transmission of hepatitis B virus from
sequence analysis of mutant HBV DNAs in two
Chinese families. Lancet, 1990;336:208-12.
Qureshi H. Post exposure prophylaxis of hepatitis B.
JPMA, March 1988;62-4
Nutritional anaemias. WHO Technical Report
Series, I972;502:29.
Dacies JV & Lewis SM. Practical Haematology.
Reference ranges and normal values. London, 7th
edition. Churchill Livingstone, 1991; 12.
Williams JR % Flowerdew ADS. Uptake of
immunization against hepatitis B among surgeons in
Wessex Regional Health Authority. BMJ,
:301:154.
Integrating hepatitis B vaccine into EPI programs
(WHO Special Report). Pak Paed J, 19; 17:85-7.
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.