SUCCESSFUL TREATMENT OF CUTANEOUS LEISHMANIASIS WITH INTRALESIONAL GLUCANTIME
Abstract
We performed a clinical trial to evaluate the efficacy and safety of intralesional glucantime in cutaneous leishmaniasis. Thirteen patients with cutaneous leishmaniasis were treated with intralesional glucantime using a 23-gauge needle. Each lesion was infiltrated with 1-2 ml of solution without local anaesthesia. Total number of injections was from 3 to 5, each one week apart. Resolution of the lesions was obtained in most of the patients (9 out of 13). The location and duration of the lesion did affect the outcome of treatment. The treatment was generally well tolerated. Intralesional treatment of cutaneous leishmaniasis is safe, effective and cheap, and excellent cosmetics results may be achieved.References
Bryceson A. Therapy in man. In: Peles W &
Killickkendrick R (Eds). The leishmaniasis in
biology and medicine: Vol 2, Academic Press,
London, 1987; pp 848-907.
Neva FA, Petersen E, Corsey R, et al. Observation
on local heat treatment for cutaneous
leishmaniasis. Am J Trop Med Hyg, 1984; 33:
-4.
Bassiouny A, El Meshad M, Talaat M. Et al.
Cryosurgery in cutaneous leishmaniasis. Br J
Dermatol, 1982; 107: 467-74.
Currie MA. Treatment of cutaneous leishmaniasis
by curettage. Br Med J, 1983; 287:1053-6.
El-On J, Weinrauch L, Livshin R. et al. Topical
treatment of recurrent cutaneous leishmaniasis
with ointment containing paromomycin and
metlhylbenzalkonium chloride. Br Med J, 1985;
: 704-5.
W.H.O. The leishmaniasis. Report of W.H.O.
Expert Committee. Technical Report Series 701.
Geneva: World Health Organization, 1984.
Bryceson ADM. Diffuse cutaneous leishmaniasis:
treatment. Trans Roy Soc Trop Med Hyg, 1970;
: 369-79.
Bryceson ADM. Clinical variations associated
with various taxa of leishmania. Coll. Int.
CNRS/INSERM 1984. Montpelier. IMEEE,
; pp 221-8.
Lainsus R. The American Leishmaniases: Some
observations on their ecology and epidemiology.
Trans Roy Soc Trop Med Hyg, 1983; 77:579-96.
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.