A COMPARATIVE STUDY OF VAGINAL PROSTAGLANDIN E2 PESSARIES WITH INTRAVENOUS OXYTOCIN FOR THE INDUCTION OF LABOUR AFTER SPONTANEOUS RUPTURE OF MEMBRANES
Abstract
ABSTRACT:In a prospective randomized study, 60 patients were induced with 3 mg vaginal FE2 pesseries
or intravenous oxytocin.
Oxytocin stimulation was associated with shorter labour and a lower incidence of abnormal
cervimeteric progress, after spontaneous rupture of membranes. Out of these patients given PGE2
20% required a second dose after four hours of slow progress. 10% of primigravida subsequently
developed abnormal labour and required augmentation by oxytocin to correct their uterine
contractions. Two caesarian sections were carried out for disproportion and remaining 58 patients
were delivered vaginally. PGE2 pesseries were not associated with an increased incidence of
hyperstimulation or sepsis. In conclusion oxytocin infusion is a safe, effective but inconvenient
method of induction of labour, while PGE2 pesseries are safe, effective, more acceptable but an
expensive method of induction of labour.
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