EFFECT OF GENDER ON ECHOCARDIOGRAPHIC OUTCOMES OF PATIENTS PRESENTING WITH MITRAL STENOSIS AT A TERTIARY CARE HOSPITAL

Authors

  • Muhammad Saeed
  • Inam -ul- Haq
  • Muhammad Amer Saleem

Abstract

Background: To assess the gender-based differences in the echocardiographic outcomes of patientswith mitral stenosis presenting at a tertiary care hospital and the clinical implications of suchdifferences. Methods: A total of 90 echocardiographs of both men and women (aged≥15 years) havingmitral valve area (MVA) less than 4 cm2 were assessed. In addition to MVA, pressure half time and leftatrial diameter (LAD) of the patients was also recorded. Other co-existing valvular lesions were alsoassessed in addition to mitral stenosis. Statistical analysis was done using SPSS-17. Results: A higherprevalence of mitral stenosis (MS) was found in women than men (76.66% vs 24.44%). Men werehaving more severe mitral stenosis as compared to women (MVA=1.19 cm2 vs 1.32 cm2). This alsoresulted in significantly higher left atrial dilatation in males as compared to women (45.09 vs 41.75,p=0.0422). Most of the patients had other coexisting valvular lesions and isolated MS was rare.However, men had a predominance of aortic stenosis along with mitral stenosis (27% vs 4%, p=0.0059)whereas women had a higher prevalence of mitral regurgitation along with mitral stenosis than the men(65% vs 36%, p=0.0258). Conclusion: There were certain significant differences in echocardiographicoutcomes of patients based upon their gender. A gender-specific management approach towards thepatients with mitral stenosis is essential to have better outcome.Keywords: Mitral stenosis, Rheumatic heart disease, Echocardiography, Gender

References

Turi ZG. Cardiology patient page. Mitral valve disease.

Circulation 2004;109(6):e38–41.

Carabello BA, Crawford FA Jr. Valvular heart disease. N Engl J

Med 1997;337:32–41.

Ates M, Sensoz Y, Abay G, Akcar M. Giant left atrium with

rheumatic mitral stenosis. Tex Heart Inst J 2006;33:389–91.

Hurst JW. Memories of patients with a giant left atrium.

Circulation 2001;104:2630–1.

Chiang CW, Kuo CT, Chen WJ, Lee CB, Hsu TS. Comparisons

between female and male patients with mitral stenosis. Br Heart J

;72(6):567–70.

Baumgartner H, Hung J, Bermejo J, Chambers JB, Evangelista

A, Griffin BP, et al. Baumgartner H. Echocardiographic

assessment of valve stenosis: EAE/ASE recommendations for

clinical practice. European Journal of Echocardiography

;10:1–25.

Guilherme L, Cunha-Neto E, Coelho V, Snitcowsky R,

Pomerantzeff PM, Assis RV, et al. Human heart-infiltrating T-cell

clones from rheumatic heart disease patients recognize both

streptococcal and cardiac proteins. Circulation 1995;92(3):415–20.

Agarwal BL. Rheumatic heart disease unabated in developing

countries. Lancet 1981;2:910–1.

Fairweather D, Rose NR. Women and autoimmune diseases.

Emerg Infect Dis 2004;10:2005–11.

Health and Vital Statistics 2. Vital Statistics 1990; Department of

Health, the Executive Yuan, Republic of China.

Islam AKMM, Azhar MA, Islam MF, Haque MZ, Yeasmin L. A

Clinical Study on the Pattern of Mitral Valvular Disease in a

Peripheral Tertiary Hospital in Bangladesh. Cardiovascular

journal 2010;3(1):11–21

Plowman SA, Smith DL. Exercise Physiology for Health,

Fitness, and Performance. Philedelphia; Lippincott Williams &

Wilkins: 2007.

Nakatani S, Masuyama T, Kodama K, Kitabatake A, Fujii K,

Kamada T. Value and limitations of Doppler echocardiography

in the quantification of stenotic mitral valve area: comparison of

the pressure half-time and the continuity equation methods.

Circulation 1988;77:78–85.

Published

2011-06-01

Issue

Vol. 23 No. 2 (2011): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

License

Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License  CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.

USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.

AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.

Most read articles by the same author(s)