SEASONAL VARIATIONS ON SERUM GLUCOSE AND LIPID PROFILE IN A MALE POIKILOTHERM VERTEBRATE, UROMASTYX HARDWICKII

Authors

  • Ghazala Qureshi
  • Tanvir Shirwany

Abstract

Background: Uromastyx hardwickii, a local lacertilian species, is widely distributed in the Indo-Paksubcontinent and inhabits mostly the arid regions of the country. This study was carried out to assessthe seasonal variations on glucose, cholesterol and triacylglycerol (TAG) levels in a poikilothermvertebrate species and to develop an experimental model for the study of lipid metabolism in highervertebrates including mammals. Methods: This cross-sectional study was carried out on maleUromastyx hardwickii. Sixty animals were bled and sacrificed within 48 hrs of their arrival in thelaboratory. Blood samples were collected by anterior abdominal venepuncture from conscious animalsusing a heparinised syringe. Results: Mean serum TAG levels were significantly higher in summer,while no significant changes were seen in cholesterol level during different parts of the year. Meanserum glucose levels were significantly higher in summer. Conclusion: Lipid metabolism inUromastyx hardwickii undergoes significant seasonal alteration. There is significant (p<0.05) increasein serum triglycerides during summer. Similarly, serum glucose also exhibits seasonal variation.Keywords: Uromastyx hardwickii, animal model, lipid profile, seasonal, triglyceride

References

Coz-Rakovac Rozelindra, Duje Lisicic, Tomislav Smuc, Natalija

Topic Popovic, Ivancica Strunjak-Perovic, Margita Jadan, et al.

Classification Modeling of Physiological Stages in Captive

Balkan Whip Snakes using blood biochemistry parameters. J

Herpetology 2011;45(4):525–9.

Abu-Zinadah OA. Variation in testicular histology of the spinytailed lizard Uromastix Aegyptius Microlepis during hibernation

and active periods. Pak J Biol Sci 2008;11(12):1615–9.

Bhaktaraj B, Patil S, Patil SB. GnRH and/or testosterone induced

changes in reproductive activities during non-breading season in

Calotes versicolor (Daud.). Indian J Exp Biol 2000;38(9):873–6.

Lance VA, Place AR, Grumbles JS, Rostal DC. Variation in

plasma lipids during the reproductive cycle of male and female

desert tortoises, Gopherus agassizii. J Exp Zool 2002;293:703–11.

Simandle ET , Espinoza RE, Nussear KE, Tracy CR. Lizards,

Lipids and dietary links to animal function. Physiol Biochem

Zool 2001;74:625–40.

Guillete LJ, Andreu GC. Seasonal variations in fat body weights

of the Mexican High Elevation Lizard Sceloporus grammicus

microlepidotus. Herpetology 1981;15:366–72.

Xiang JI, Peichao W. Annual cycles of lipid contents and caloric

values of carcass and some organs of the Gecko Gekko

Japonicus. Comp Biochem Physiol 1990;19:267–71.

Firth BT, Belan I. Daily and seasonal rhythms in the selected

body temperatures in the Australian Lizard Tiliqua Rugosa

(Scincidae): Field and Laboratory observations. Physiol Biochem

Zool 1998;303–11.

Nedergaard J, Cannon B. Preferential utilization of brown

adipose tissue lipids during arousal from hibernation in hamsters.

Am J Physiol 1984;247:506–12.

Bertelsen MF, Kjelgaard-Hansen M, Howell JR, Crawshaw GJ.

Short-term biological variation of clinical chemical values in

Dumeril’s monitors. J Zoo Wildl Med 2007;38(2):217–21.

Published

2012-06-01

Issue

Vol. 24 No. 2 (2012): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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