USING ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING APPROACHES TO ENHANCE CANCER THERAPY AND DRUG DISCOVERY
DOI:
https://doi.org/10.55519/JAMC-01-12921Keywords:
Cancer therapy, Machine learning, Drug discoveryAbstract
This paper looks at how AI and machine learning have been applied over the last ten years to the development of anti-cancer drugs. By speeding up the synthesis of more desirable compounds and the identification of new ones, artificial intelligence (AI) has demonstrated substantial contributions to the research and therapy of anti-cancer therapies. Future developments in human cancer research and treatment are anticipated to be significantly influenced by AI. Protein-interaction network analysis, drug target prediction, binding site prediction, and virtual screening are examples of innovative techniques. Drug design and screening are enhanced by machine learning, and the use of multitarget drug development approaches has made it possible to develop cancer treatments with fewer side effects. AI does, however, have several drawbacks, such as a heavy reliance on data and a narrow scope of explanation. Interpretable AI models, which combine data and computation in AI-assisted cancer treatment research, will be the new development path in the future. For more than thirty years, computer-aided drug design techniques have been a key component in the advancement of cancer therapies. Artificial intelligence is a new and powerful technology that has the potential to speed up, lower the cost, and improve the efficacy of anti-cancer therapy development. This work is a narrative review that examines numerous uses of AI-based techniques in the development of anti-cancer medications. We go on to explain the underlying ideas of these techniques as well as their benefits and drawbacks. In addition, we aggregate a multitude of databases, such as the pharmacological, chemical compound, omics, and epigenomics databases. They can be taken into consideration and modified to suit the needs of other researchers.References
Kumar, R., Saha, P., Kumar, Y., Sahana, S., Dubey, A., & Prakash, O. (2020). A Review on Diabetes Mellitus: Type1 & Type2. World Journal of Pharmacy and Pharmaceutical Sciences, 9(10), 838-850.
Saha, P., Nyarko, R. O., Lokare, P., Kahwa, I., Boateng, P. O., & Asum, C. (2022). Effect of Covid-19 in Management of Lung Cancer Disease: A Review. Asian Journal of Pharmaceutical Research and Development, 10(3), 58-64.
Daharia, A., Jaiswal, V. K., Royal, K. P., Sharma, H., Joginath, A. K., Kumar, R., & Saha, P. (2022). A Comparative review on ginger and garlic with their pharmacological Action. Asian Journal of Pharmaceutical Research and Development, 10(3), 65- 69.
Singh, M. K., Kumar, A., Kumar, R., Kumar, P. S., Selvakumar, P., & Chourasia, A. (2022). Effects of Repeated Deep Frying on Refractive Index and Peroxide Value of Selected Vegetable Oils. International Journal for Research in Applied Sciences and Biotechnology, 9(3), 28-31
Roshan, K. (2020). Priya damwani, Shivam kumar, Adarsh suman, Suthar Usha. An overview on health benefits and risk factor associated with coffee. International Journal Research and Analytical Review, 7(2), 237-249.
Kumar, R., Saha, P., Lokare, P., Datta, K., Selvakumar, P., & Chourasia, A. (2022). A Systemic Review of Ocimum sanctum (Tulsi): Morphological Characteristics, Phytoconstituents and Therapeutic Applications. International Journal for Research in Applied Sciences and Biotechnology, 9(2), 221-226.
Nyarko, R. O., Kumar, R., Sharma, S., Chourasia, A., Roy, A., & Saha, P. (2022). ANTIBACTERIAL
ACTIVITY OF HERBAL PLANT-TINOSPORA CORDIFOLIA AND CATHARNTHUS ROSEUS.
Sahana, S. (2020). Purabi saha, Roshan kumar, Pradipta das, Indranil Chatterjee, Prasit Roy, Sk Abdur Rahamat. A Review of the 2019 Corona virus (COVID- 19) World Journal of Pharmacy and Pharmaceutical science, 9(9), 2367-2381
Bind, A., Das, S., Singh, V. D., Kumar, R., Chourasia, A., & Saha, P. Natural Bioactives For The Potential Management Of Gastric Ulceration. Turkish Journal of Physiotherapy and Rehabilitation, 32(3).
Dubey, A., Yadav, P., Verma, P., & Kumar, R. (2022). Investigation of Proapoptotic Potential of Ipomoea carnea Leaf Extract on Breast Cancer Cell Line. Journal of Drug Delivery and Therapeutics, 12(1), 51-55.
Saha, P., Kumar, R., Nyarko, R. O., Kahwa, I., & Owusu, P. (2021). HERBAL SECONDARY METABOLITE FOR GASTRO-PROTECTIVE ULCER ACTIVITY WITH API STRUCTURES.
Sahana, S. (2020). Roshan kumar, Sourav nag, Reshmi paul, Nilayan guha, Indranil Chatterjee. A Review on Alzheimer disease and future prospects. World Journal of Pharmacy and Pharmaceutical science, 9(9), 1276-1285.
Sahana, S., Kumar, R., Nag, S., Paul, R., Chatterjee, I., & Guha, N. (2020). A REVIEW ON ALZHEIMER DISEASE AND FUTURE PROSPECTS.
Nyarko, R. O., Prakash, A., Kumar, N., Saha, P., & Kumar, R. (2021). Tuberculosis a globalized disease. Asian Journal of Pharmaceutical Research and Development, 9(1), 198-201.
Kumar, R., & Dubey, A. PHYTOCHEMICAL INVESTICATION AND HEPTOPROTECTIVE EVALUTION ACACIA RUBICA EXTRACT ISONIZED AND PARACETAMOL INDUSED ANIMAL TOXICITY. Turkish Journal of Physiotherapy and Rehabilitation, 32(3).
Raj, A., Tyagi, S., Kumar, R., Dubey, A., & Hourasia, A. C. (2021). Effect of isoproterenol and thyroxine in herbal drug used as cardiac hypertrophy. Journal of Cardiovascular Disease Research, 204-217.
PURABISAHA, R. K., RAWAT, S. S. N., & PRAKASH, A. (2021). A REVIEW ON NOVEL DRUG DELIVERY SYSTEM.
Nyarko, R. O., Saha, P., Kumar, R., Kahwa, I., Boateng, E. A., Boateng, P. O., ... & Bertram, A. (2021). Role of Cytokines and Vaccines in Break through COVID 19 Infections. Journal of Pharmaceutical Research International, 33, 2544-2549.
Kumar, R., Saha, P., Pathak, P., Mukherjee, R., Kumar, A., & Arya, R. K. EVOLUTION OF TOLBUTAMIDE IN THE TREATMENT OF DIABETES MELLITUS. Jour. of Med. P’ceutical & Alli. Sci, 9.
KUMAR, R., SAHA, P., SARKAR, S., RAWAT, N., & PRAKASH, A. (2021). A REVIEW ON NOVEL DRUG DELIVERY SYSTEM. IJRAR-International Journal of Research and Analytical Reviews (IJRAR), 8(1), 183-199.
KUMAR, A. (2019). The Scenario of Pharmaceuticals and Development of Microwave Assisted Extraction Techniques.
SHAFQAT ZAIDI, R. K. MEHRA, Dr. SACHIN TYAGI, ROSHAN KUMAR ANUBHAV DUBEY.(2021). Effect of Kalahari Cactus Extract on Appetitte, Body Weight And Lipid Profile In Cafeteria Diet Induced Obesity In Experimental Animal. Annals of the Romanian Society for Cell Biology, 25(6), 13976- 13987.
Markham, A. (2017). Copanlisib: first global approval. Drugs, 77(18), 2057-2062.
Mathi, P., Prasad, M. V. V. V., Botlagunta, M., Ravi, M., & Ramachandran, D. (2018). De novo design of selective Sortase-A inhibitors: Synthesis, structural and in vitro characterization. Chemical Data Collections, 15, 126-133.
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