A NEW ASSOCIATION OF GUILLAIN BARRE SYNDROME IN A PATIENT WITH CENTRAL NERVOUS SYSTEM MELIOIDOSIS

Authors

  • Ewe Jin Koh Department of Internal Medicine, Hospital Taiping
  • Kah Nian Tan Department of Internal Medicine, Hospital Taiping
  • Zhi Wei Chan Department of Internal Medicine, Hospital Taiping
  • Hoy Yan Candice Wong Department of Internal Medicine, Hospital Taiping
  • Ming Lee Chin Department of Medicine and Paediatrics
  • Tiong Chan Lee Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia

DOI:

https://doi.org/10.55519/JAMC-02-11470

Keywords:

Melioidosis, Peripheral nervous system, Acute flaccid paralysis, Anti-ganglioside antibodies, Guillain Barre sydrome

Abstract

Burkholderia pseudomallei affecting the central nervous system has been extensively reported in the literature. However, combined central nervous system and peripheral nervous system involvement in melioidosis has never been reported. We report a 66-year-old man with diabetes mellitus who was diagnosed to have central nervous system melioidosis and developed acute flaccid quadriplegia. Nerve conduction studies and anti-ganglioside antibodies were consistent with Guillain-Barre syndrome. This case report highlights the importance to recognise the possibility of Guillain Barre syndrome complicating central nervous system melioidosis and stresses the urgency of early consideration of this complication, as early immunomodulatory therapy may hasten neurological recovery.

Author Biographies

Ewe Jin Koh, Department of Internal Medicine, Hospital Taiping

Internal Medicine Specialist

Kah Nian Tan, Department of Internal Medicine, Hospital Taiping

Medical Officer

Zhi Wei Chan, Department of Internal Medicine, Hospital Taiping

Medical Officer

Hoy Yan Candice Wong, Department of Internal Medicine, Hospital Taiping

Medical Officer

Ming Lee Chin, Department of Medicine and Paediatrics

Specialist

Tiong Chan Lee, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia

Consultant Internal Medicine Physician

References

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Published

2023-04-17

How to Cite

Koh, E. J., Tan, K. N., Chan, Z. W., Wong, H. Y. C., Chin, M. L., & Lee, T. C. (2023). A NEW ASSOCIATION OF GUILLAIN BARRE SYNDROME IN A PATIENT WITH CENTRAL NERVOUS SYSTEM MELIOIDOSIS. Journal of Ayub Medical College Abbottabad, 35(2). https://doi.org/10.55519/JAMC-02-11470

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