OPSOCLONUS-MYOCLONUS-ATAXIA SYNDROME (OMAS) DUE TO ORGANOPHOSPHATE TOXICITY: CASE REPORT OF A RARE ASSOCIATION

Authors

  • Dur-e-Sabeh Bahawal Victoria Hospital, Quaid-e-Azam Medical College Bahawalpur-Pakistan
  • Nauman Ismat Butt Azra Naheed Medical College, Superior University Lahore-Pakistan
  • Muhammad Sohail Ajmal Ghoauri Bahawal Victoria Hospital, Quaid-e-Azam Medical College Bahawalpur-Pakistan
  • Asfand Yar Ali Bahawal Victoria Hospital, Quaid-e-Azam Medical College Bahawalpur-Pakistan
  • Fahad Qaisar Bahawal Victoria Hospital, Quaid-e-Azam Medical College Bahawalpur-Pakistan
  • Muhammad Umair Javed Bahawal Victoria Hospital, Quaid-e-Azam Medical College Bahawalpur-Pakistan

DOI:

https://doi.org/10.55519/JAMC-01-13103

Keywords:

Opsoclonus-Myoclonus-Ataxia Syndrome (OMAS), Organophosphate Toxicity, Opsoclonus, Myoclonus, Ataxia.

Abstract

Opsoclonus-Myoclonus-Ataxia Syndrome (OMAS) is a rare neurological disorder characterized by severe ataxia, multifocal muscle jerky movements and rapid eye oscillatory movements rarely seen as a consequence of organophosphate exposure. A 19-year-old gentleman presented with 2-day history of sudden onset uncontrollable jerky movements of all four limbs, dizziness and vertigo, difficulties in sitting and walking characterized by side-way swaying and increased tendency to fall. There was history of palpitations, vomiting, diarrhea, increased urination, lacrimation and salivation. Four days prior to presentation, there was accidental exposure to chlorpyrifos. On examination, pooling of tears, dribbling of saliva, hypertension, tachycardia, miosis, opsoclonus, myoclonus and ataxia were noted. He was admitted and started on intravenous atropine. MRI scan was done which demonstrated normal cerebellum. He was diagnosed with OMAS caused by Organophosphate Toxicity. By the time of discharge, he was clinically stable and asymptomatic.

Author Biography

Nauman Ismat Butt, Azra Naheed Medical College, Superior University Lahore-Pakistan

Correspondence:

Department of Medicine & Allied, Azra Naheed Medial College, Superior University Lahore-Pakistan

Cell: +92 345 465 1049

Email: nauman_ib@yahoo.com

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Published

2025-03-15

How to Cite

1.
Dur-e-Sabeh, Butt NI, Ghoauri MSA, Ali AY, Qaisar F, Javed MU. OPSOCLONUS-MYOCLONUS-ATAXIA SYNDROME (OMAS) DUE TO ORGANOPHOSPHATE TOXICITY: CASE REPORT OF A RARE ASSOCIATION. J Ayub Med Coll Abbottabad [Internet]. 2025 Mar. 15 [cited 2025 Aug. 24];37(1):186-8. Available from: https://www.jamc.ayubmed.edu.pk/index.php/jamc/article/view/13103