EFFECT OF EXAMINATION STRESS ON BLOOD CELL PARAMETERS OF STUDENTS IN A PAKISTANI MEDICAL COLLEGE

Authors

  • Faiyaz Qureshi
  • Jane Alam
  • Masood Ahmad Khan
  • Ghazala Sheraz

Abstract

Background: Physiological studies show that stress can alter the blood cells parameters in healthy individuals. We tried to determine whether exams in medical schools are stressful enough to produce such changes. Methods: A randomized selection of female students from Women Medical College, Abbottabad, Pakistan, was carried out. After preliminary medical checkup blood samples were taken before and during exams. Students having temperature or high blood pressure at the start of study were excluded. Finally 37 students were included. Estimations of red blood cells, hematocrit, neutrophils, lymphocytes, eosinophils, monocytes, basophils and platelets were carried out. Results: Compared with pre-examination results the blood samples taken during exams showed a significant decrease in eosinophil, basophil, lymphocyte and monocyte count. An increase in platelet and neutrophil count was also observed. No significant changes were observed in red blood cell and hematocrit readings. Conclusion: It is concluded that examinations in medical schools are stressful enough to produce changes in blood cells parameters which include increase in neutrophils, and platelets, while eosinophils, monocytes basophils and lymphocytes decreased in number

References

Maes M,Van der Planken M, Van Gastel A, et al. Influence of academic stress on hematological measurements in subjectively healthy volunteers. Psychiatry Res 1998;80:201-212.

Benoit D, Esa L, Ralph G. The driving test as a stress model: Effects on blood picture, serum cortisol and the production of interleukins in man. Life Sci 2001 Feb 23;68(14):1641-7.

Dacie J.V, Lewis S.M.(1991), Practical Hematology, 7th Ed. Page77.

Dhabhar FS, Miller AH, McEwen BS, Spencer RL. Effects of stress on immune cell distribution. Dynamics and hormonal mechanisms. J Immunol 1995 May 15;154 (10):5511-27.

Marshall GD, Agarwal SK. Stress, immune regulation and immunity: Applications for asthma. Allergy Asthma Proc 2000 Jul-Aug;21(4):241-6.

Broxmeyer H. Role of cytokines in hemotopoiesis. In: Agarwal B (ed). Human cytokines: their role in disease and therapy. Blackwell Science, 1995,pp. 27-36.

Smith J, Telford R, Kolbuch-Braddon M, Weidemann M. Lactate/H+ uptake by red blood cells during exercise alters their physical properties. Eur J Appl Physiol 1997;75:54-6

Issue

Vol. 14 No. 1 (2002): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

License

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