IDENTIFIABLE RISK FACTORS IN HEPATITIS B AND C

Authors

  • Faiz -Ur- Rehman
  • Jehangir Khan
  • Zahid Fida
  • Arshad Parvez
  • Ahmad Rafiq
  • Shandana Syed

Abstract

Background: Both hepatitis B and C are common infections affecting masses and are leading causes ofChronic Liver Disease in Pakistan as well as worldwide. In majority of cases both viral diseases spreadby factors that are preventable. The present study is conducted to determine the identifiable risk factorsin patients admitted with Chronic Hepatitis B and C. Methods: An observational study was carried outfor a period of 6 months. All age groups and both sexes were included. The patients were interviewedand the identifiable risk factors were looked for. The standard methods for detection of Hepatitis B andC were used. Results: One-hundred and ten patients were studied from January to July 2009. Sixty-fivepatients had Hepatitis C, 35 had Hepatitis B, and 10 had both Hepatitis B and C. Ninety-three patientshad a history of injections and transfusions etc., and 38 had surgical scars. Tattoos were present in 42patients and nose and/or ear piercing marks were present in 28 patients. The number of risk factorsincreased in co-infection. Conclusion: There is a role of unhygienic health delivery practices, lack ofawareness and resources for standard screening protocol for spread of Hepatitis B and C.Keywords: Hepatitis B, Hepatitis C, risk factors, prevention, identifiable, awareness

References

Abbas Z, Jafri W, Shah SH, Khokhar N, Zuberi SJ. PGS

consensus statement on management of hepatitis B virus

infection-2003. J Pak Med Assoc 2004;54:150–8.

Hamid S, Umar M, Alam A, Siddiqui A, Qureshi H, Butt J. PSG

consensus statement on management of hepatitis C virus

infection-2003. J Pak Med Assoc 2004;54:146–50.

Bari A, Akhtar S, Rahbar MH, Luby SP. Risk factors for hepatitis

C virus infection in male adults in Rawalpindi-Islamabad,

Pakistan. Trop Med Int Health 2001;6:732–8.

Khan F, Shams S, Qureshi ID, Israr M, Khan H, Sarwar MT, et

al. Hepatitis B virus infection among different sex and age groups

in Pakistani Punjab. Virol J 2011;8:225.

Jittiwutikarn J, Thongsawat S, Suriyanon V, Maneekarn N,

Celentano D, Razak MH, et al. Hepatitis C infection among drug

users in northern Thailand. Am J Trop Med Hyg 2006;74:1111–6.

Perez CM, Suarez E, Torres EA, Roman K, Colon V.

Seroprevalence of hepatitis C virus and associated risk

behaviours: a population-based study in San Juan, Puerto Rico.

Int J Epidemiol 2005;34:593–9.

Usman HR, Akhtar S, Rahbar MH, Hamid S, Moattar T, Luby

SP. Injections in health care settings: a risk factor for acute

hepatitis B virus infection in Karachi, Pakistan. Epidemiol Infect

;130:293–300.

Pakistan Medical Research Council. National survey on

prevalence of hepatitis B and C in general population of Pakistan.

Available from: www.pmrc.org.pk/hepatitisbc.html

Hugo R, Rosen MD. Chronic Hepatitis C Infection. N Engl J

Med 2011;364:2429–38.

Frank C, Mohammad MK, Strickland GT, Lavanchy D, Arthur

RR, Magder LS, et al. The role of parenteral antishcistosomal

therapy in the spread of hepatitis C virus in Egypt. Lancet

;355:887–91.

Andre F. Hepatitis B epidemiology in Asia, the Middle East and

Africa. Vaccine 2000;18 (Suppl 1):S20–2.

Khan AA, Rehman K, Haider Z, Shafqat F. Seromarkers of

hepatitis B and C in Pakistan with cirrhosis. J Coll Physicians

Surg Pak 2002;12(2):105–7.

Chohan AR, Umar M, Khaar B. Demographic features of

hepatocellular: a study of 30 cases. J Rawalpindi Med Coll

;5:81–3.

Macedo de Oliviera A, White KL, Leschinsky DP, Beecham BD.

An outbreak of hepatitis C virus infection in outpatients at a

hematology/oncology clinic. Ann Int Med 2005;142(11):898–902.

Zaller N. Nelson KE Aladashvili M. Risk factors for Hepatitis C

viral infection among blood donors in Georgia. Eus Epidermal

;19(6):547–53.

Cecere A, Marotta F, Lucariello A, Tancredi L, Vangieri B,

Gattoni A. High prevalence of hepatitis C virus infection in a

Southern Italian rural region. Clinical aspects and evidence of in

apparent parenteral exposure. Pan Minerva Med. 2003;45:253–9

Ali M, Idrees M, Ali L, Hussain A, Ur Rehman I, Saleem S, et

al. Hepatitis B virus in Pakistan; A systematic review of

prevalence, risk factors, awareness, status and genotypes. Virol J

;8:102.

She SL, Shi LY, Wu YJ, Li ZZ, Zheng CZ, Wu YP, et al. A

seroepidemiologic study of hepatitis B virus infection among

Barbers in Huangshi City, Heubi China. Microbiol Immunol

;32:229–33.

Judd A, Hutchinson S, Wadd S, Hickman M, Taylor A, Jones

S, et al. Prevalence of, and risk factors for, hepatitis C virus

infection among recent initiates to injecting in London and

Glasgow: cross sectional analysis. J Viral Hepatol

;12(6):652–62.

Kwiatkowsin CF. Fortyvin Cursie, Booth RE. The association

between knowledge of Hep C virus status risk behavior in

addiction. 2002;97(10):1289–94.

Dore GJ, Law M, Mac Donald M, Kaldor JM. Epidemiology of

Hepatitis C virus infection in Aus J Clinical Virol

;26(2):171–84.

Gunn RA, Murray PJ, Ackers ML, Hardison WG, Margolis HS.

Screening for chronic hepatitis B and C viral infections in an

urban sexually transmitted disease clinic. Sex Transm Dis

;28(3):166–70.

Syriopoulou V, Nikolopoulou G, Daikos GL, Theodoridou

M, Pavlopoulou I, Nicolaidou P, et al. Mother to child

transmission of hepatitis C virus: rate of infection and risk factors.

Scand J Infect Dis 2005;37:350–3.

Published

2011-12-01