AETIOLOGY AND TYPES OF NEONATAL SEIZURES PRESENTING AT AYUB TEACHING HOSPITAL ABBOTTABAD

Shahzad Najeeb, Azhar Munir Qureshi, Anis -ur- Rehman, Fayaz Ahmad, Sher Shah, Asfand Yar Khan, Tahir Saeed Siddiqui

Abstract


Background: Neonatal seizures (NS) affect approximately 1% of neonates. Clonic, tonic, myoclonic
and subtle seizures are the common types. Birth asphyxia, sepsis, metabolic derangements, intracranial
bleed, kernicterus, tetanus and 5th day fits are the common aetiologies. This study was planned to
evaluate the types and causes of neonatal seizures. Methods: It was a descriptive case series conducted
at Ayub Teaching Hospital, Abbottabad from 12th December 2006 to 25th September 2007 on neonates
having seizures. Serum chemistry, blood counts, cerebrospinal fluid examination and cranial ultrasound
were done in all patients. Blood culture, renal and liver function tests, computerised tomography scan,
metabolic and septic screening was done in selected patients. Descriptive statistics were applied for
analysis. Results: Tonic clonic seizure was the commonest type (28%) followed by multi-focal clonic,
and focal tonic seizures (25% each). Birth asphyxia was found to be the main aetiology (46%).
Conclusion: Tonic clonic seizure was the commonest type and birth asphyxia the main aetiology
identified in the majority of neonatal seizures.
Keywords: Neonatal seizures, Aetiology, Seizures, Epilepsy, Neonates

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