FREQUENCY OF PERIPHERAL NEUROPATHY IN PATIENTS WITH DIABETES MELLITUS
Abstract
Background: The main purpose of this study was to ascertain the frequency of peripheral diabetic neuropathy in diabetic patients and to stratify the different variants of peripheral neuropathy in patients. Methods: Two hundred and fifty diabetic patients presenting to diabetic management centre, were included in this cross sectional study. Effect modifier (duration of diabetes) were studied through stratification. Eleven point neuropathic pain scale was used to access the extent of neuropathy. Results: The frequency of neuropathy in diabetic patients was 187 (74.8%). Out of 250 patients 116 (46.4 %) patients were found to have burning type of pain and 114 (45.6%) were found to have numbness while 61 (24.4%) had tingling. Out of 250 patients 17 (6.8%) were found to have sharp pain and 55 (22%) had dullness. Out of 250 patients 44 (17.6%) had coldness. Ten patients (4%) out of 250 had sensitive type of pain. frequency of itchy type of pain was 6.4%. Conclusion: The study showed that painful diabetic neuropathy is present in majority of controlled diabetics and most of them belong to old age. It further showed that majority of sufferer were females. The most common variety of pain encountered was burning type of pain.Keywords: Diabetes mellitus, Diabetic peripheral neuropathyReferences
Umesh M. Diabetes mellitus and hypoglycemia. In: Tierney LM, McPhee SJ, Papadakis MA, editors. Current medical diagnosis and treatment. 48th ed. New York: Mc Graw- Hill; 2009.p. 1032–73.
Muniz EC, Rocha RM, Reis ML, Santos VL, Grossi SA. Neuropathic and ischemic changes of the foot in Brazilian patients with diabetes. Ostomy Wound Manag 2003;49:60–70.
Hashim R, Ahmed KF, Ahmed KD, Shaukat A. Prevalence of Microvascular complications of Diabetic patients. J Coll Physicians Surg Pak 1999;9(3):120–2.
Kirwin JL, Cunningham RJ, Sequist TD. Pharmacist recommendations to improve the quality of diabetes care: a randomized controlled trial. J Manag Care Pharm 2010;16:104–13.
Mehboob F, Majeed MZ, Zaman SM. An impact of life style and obesity on diabetes. Hypertension and Hyperlipidemia. J Fatima Jinnah Medical Coll Lahore 2007;1(3–4):59–63.
Gale EAM, Anderson JV. Diabetes mellitus and other disorders of metabolism. In: Kumar P, Clark M, editors. Clinical medicine, editors. 6th ed. Edinburgh, United Kingdom: WB Saunders; 2005.p.1101–51.
Wilson JD. Approach to the patient with endocrine and metabolic disorders. In: Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, editors. Harrison’s principles of internal medicine. 14th ed. New York: Mc Graw-Hill; 1998.p. 2074–5.
Mendill JR, Sehank Z. Painful sensory neuropathy. N Engl J Med 2003;348:1243–55.
Wong WT, Wong SL, Tian XY, Huang Y. Endothelial dysfunction: the common consequence in diabetes and hypertension. Cardiovasc Pharmacol 2010;55:300–7.
Boulton AJM, Malik RA, Arezzo JC, Sosenko NJ. Diabetic somatic neuropathies: technical review. Diabetes Care 2005;427:1458–86.
Boulton AJM, Vinik AI, Arezzo JC, Bril V, Feldman EL, Freeman R, et al. Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes Care 2005;28:956-62.
Vileikyte L, Rubin RR, Leventhal H: Psychological aspects of neuropathic foot complications: an overview. Diabete Metab Res Rev 2004;20:S13–18.
Obrosova IG. Diabetic painful and insensate neuropathy: pathogenesis and potential treatments. Neurotherapeutics 2009;6:638–47.
Girach A, Vignati L. Diabetic microvascular complications-can the presence of one predict the development of another? J Diabetes Complications. 2006;20:228–37.
Vinik AI, Mehrabyan A. Diabetic neuropathies. M Clin N Am 2004;88:947–9.
Ziegler D, Nowak H, Kempler P, Vargha P, Low PA. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis. Diabet Med 2004;21:114–21.
Argoff CE; Cole BE, Fishbain DA; Irving GA. Diabetic peripheral neuropathic pain: clinical and quality-of-life issues. Mayo Clin Proc 2006; 81: S3-S11.
Soyupek F, Ceceli E, Suslu FE, Yorgancıoglu R. Neurologic and radiologic abnormalities of the foot in diabetic patients. J Back Musculoskelet Rehabil 2007;20:55–¬60
Published
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.
